My new book, “The Miracles Among Us,” reveals multiple miracles that have lifted my spirits throughout the writing process and have also successfully raised the spirits of many readers who have reached out to share their own miracles since its publication in November. That theme offers hope for 2026 – that faith and God’s continued guiding presence can help us overcome our divisions. Here is my list of five miracles of 2025 that make me optimistic about the coming new year.
1. The hostages
Eli Sharabi was taken hostage by Hamas on October 7, 2023 and released on February 8, 2025 as part of a peace deal, only to discover that his wife Lianne; their daughters Noiya and Yahel; and his brother Yossi – who was also held hostage – had been murdered.
Sharabi’s memoir ‘Hostage’ is an incredible portrayal of the terrible suffering, torment, hardship and dehumanization he suffered at the hands of his Hamas captors.
After his release, Sharabi became an advocate for the return of the remaining hostages and the return of the dead still in the hands of Hamas.
DR. MARC SIEGEL: TELL ME YOUR MIRACLES, AND I’LL TELL YOU WHAT I PRAY FOR
Sharabi’s survival – and that of the 168 other hostages returned alive to Israel – is a great miracle. He has spoken about how Jewish teachings and the Torah helped him choose life rather than allow grief and loss to bury him.
As we enter 2026, we pray for lasting peace in Gaza, in Israel and throughout the Middle East.
2. Medical breakthroughs
In the medical world, advances in cancer immunotherapy are miraculous and promising for 2026. Cancer vaccines, including mRNA-based therapies, now target proteins on the surface of the cancer, opening the door to further targeted therapies such as antibody-drug conjugates. These therapies have shown effectiveness against previously untreatable tumors, including pancreatic cancer.
One important target is the KRAS gene, which is prominent in many cases of pancreatic cancer. KRAS is responsible for regulating cell growth through a protein that acts as a cellular switch, but a mutation causes the switch to remain ‘on’, causing the cancer to spiral out of control.
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We are entering an era of personalized cancer treatments, where a person’s specific genetic makeup determines both prevention and treatment therapies.
3. Artificial intelligence
There has been much discussion and debate about artificial intelligence, but from my perspective the promise is simply a no-brainer. From Nvidia-designed robots that understand and perform complex tasks – including moving, lifting, sensing, navigating and even decision-making – it is clear that robots programmed with AI will play increasingly useful roles in 2026, including patient monitoring.
Dr. Marc Siegel is the author of the new book ‘The Miracles Among Us’. (FNC)
AI is gaining traction in the world of healthcare, from the advancement of opportunistic imaging, which allows early diagnosis of heart disease and cancer without direct human intervention, to practice management and accelerated drug development. AI has revolutionized the medical world in 2025, and many more miracles will follow.
4. NexoBrid
When I wrote about Nexobrid in “The Miracles Among Us,” it was because the treatment saved many lives among burn victims after the October 7, 2023 Hamas attacks.
One family, the Golans, were literally burned alive in their kibbutz house and survived. They were healed with the help of NexoBrid.
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NexoBrid removes the dead tissue from a burn, often eliminating the need for surgical debridement. By 2025, mainstream use has spread around the world, including widespread use in the US
Now, a new study from Israel reveals that NexoBrid improves the cosmetic and healing outcomes of so-called traumatic tattoos, which involve projectile or skin damage resulting from explosive injuries.
NexoBrid, which is derived from pineapple, represents a major medical advance.
5. Baby KJ Muldoon
Baby KJ is a Christmas miracle, surviving an otherwise fatal genetic disorder that causes the buildup of uremia that the kidneys must filter from the body and leads to a massive buildup of toxic ammonia. But CRISPR genetic editing fixed KJ’s genetic mutation.
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She has been able to walk and thrive. Her experience bodes well for personalized gene therapies of many types involving a range of diseases. These miracles will become much more common in 2026 and offer more hope for the future of personalized medicine.
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